Population
Normal human thyroid tissue and autonomous nodules
Comparison
Various biochemical agents including TSH… vs Normal tissue vs autonomous nodules, and…
Design
Preclinical
Authors
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Altered sensitivities in nodular tissue should not change practice; hypothesis-generating for cAMP/cGMP-targeted therapies in human thyroid autonomy.
The study maps the biochemical regulation of human thyroid tissue via cAMP/cGMP pathways and highlights altered receptor sensitivities in autonomous nodules.
Sande et al. (1980) studied this question.
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