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July 1, 2022Open Access

Prognostic Significant of Neutrophil: Lymphocyte Ratio, Platelet – Lymphocyte ratio, and Lymphocyte – Monocyte ratio in Kurdish Patients with breast cancer

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Authors

SKSomayeh KhazaeiMTMitra TarlanSMSamineh Madani

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Overview

Retrospective study finds no significant link between blood inflammatory ratios and overall survival in breast cancer, suggesting limited prognostic utility.

Key Points

  • To evaluate the prognostic impact of neutrophil-to-lymphocyte ratio (NLR), derived NLR (dNLR), platelet-to-lymphocyte ratio (PLR), and lymphocyte-to-monocyte ratio (LMR) on overall survival in breast cancer patients.
  • Retrospectively analyzed patients diagnosed with primary breast cancer between 2004 and 2020.
  • Evaluated baseline patient characteristics and investigated the association between inflammatory markers (NLR, dNLR, PLR, LMR) and overall survival.
  • Overall survival rates were 96% at one year, 83% at three years, 78% at five years, and 63% at ten years (an interim rate of 71% was also reported).
  • Overall survival was significantly associated with tumor staging, lymph node involvement, and distant metastasis.
  • Baseline blood inflammatory ratios (PLR, NLR, dNLR, and LMR) showed no statistically significant differences or association with patient prognosis.

Cite This Study

Khazaei et al. (2022) studied this question.

synapsesocial.com/papers/6a72697e26a7f98052de48ebhttps://doi.org/10.32113/wcrj_20227_2365
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Also Consider

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  1. 1The Prognostic Significance of the Serum Inflammatory Marker Ratios, Neutrophil-Lymphocyte, Platelet-Lymphocyte and Monocyte-Lymphocyte in Male Breast Cancer.2025
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  4. 4Predictive significance of inflammatory markers in the survival of older Indian patients with cancer: a single-center prospective analysis2024 · 2 citations
  5. 5Collective neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio symbolizes a new prognostic factor in the survival of gastric cancer patients2024 · 1 citations