The removal of an eye in newborn ratsresults in an increased uncrossed optic projection from the intact eye to subcortical visual centers. The additional uncrossed projection arises from areas of retina which would normally project only contralaterally and terminates in regions of geniculate and colliculus which would normally receive only crossed optic axons. The increased projection does not occur in animals enucleated at 10 days or older. It is suggested that the abnormal projection is due largely to axons which have not reached the optic chiasm at the time of the lesion being rerouted to the 'wrong' side of the brain.
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Lund et al. (2008) studied this question.