Why the study?
Double defibrillation has shown promising results for refractory VF/pVT out-of-hospital cardiac arrest, but its efficacy, safety, and optimal strategy remain unclear due to a paucity of evidence.
Does double defibrillation improve resuscitative parameters, survival rates, and neurological outcomes in adults with refractory VF/pVT out-of-hospital cardiac arrest?
Does double defibrillation improve resuscitative parameters, survival rates, and neurological outcomes in adults with refractory VF/pVT out-of-hospital cardiac arrest?
This protocol outlines a planned scoping review to evaluate the efficacy, survival rates, and neurological outcomes of double defibrillation for refractory VF/pVT out-of-hospital cardiac arrest.
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DD should not yet change practice for refractory VF/pVT OHCA; leaves open optimal strategy pending definitive RCTs.
Double defibrillation (DD) has been proposed as an alternative treatment for patients with refractory ventricular fibrillation/pulseless ventricular tachycardia (VF/pVT) out-of-hospital cardiac arrest (OHCA) nonresponsive to the best current standard of care. Treatment results are promising, but the efficacy and safety of the procedure remain unclear. Currently, there is a paucity of evidence in the literature on DD suggesting the optimal strategy for treating this challenging patient population. Thus, we aim to perform a scoping review to explore the current literature addressing resuscitative parameters, survival rates, and neurological outcomes in refractory VF/pVT OHCA patients treated with DD as well as to identify gaps in the literature that may require further research. Here, we discuss the anticipated study protocol.
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Miraglia et al. (2020) studied this question.
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