Why the study?
The study was conducted to assess the factors affecting carotid artery intima-media thickness and the 10-year risk of heart disease in diabetic patients classified by carotid artery intima-media thickness.
In diabetic patients, increased carotid intima-media thickness is significantly correlated with a higher calculated 10-year risk of cardiovascular disease.
CIMT stratification may refine 10-year CVD risk estimates in diabetes; leaves open whether it improves outcomes over standard calculators.
Objective: The aim of the present study was to assess the factors affecting carotid artery intima-media thickness (CIMT) and 10-year risk of heart disease in diabetic patients classified according to CIMT. Methods: This was an analytical cross-sectional study conducted on 92 patients for 1 year. 10-year risk of heart disease was calculated using the American College of Cardiology/American Heart Association Guideline on the Assessment of Cardiovascular Risk. Based on CIMT, the subjects were classified into two groups. Group 1 contains subjects with CIMT <0.9 and Group 2 contains subjects with CIMT ≥0.9. The Mann–Whitney U-test, Pearson’s correlation, and descriptive statistics were used to compare and describe the data. The level of statistical significance was taken at p<0.05. Results: Patients with 51–60 years of age group are high in number. Males were predominantly high than their counterparts. There is a statistically significant association between total cholesterol (p=0.001), high-density lipoproteins (p=0.000), low-density lipoproteins (p=0.001), postprandial blood sugar (p=0.000), and hemoglobin 1Ac (p=0.035) with CIMT. The mean 10-year risk of heart disease in Groups 1 and 2 is 13.13±15.40 and 23.63±17.57, respectively. There is statistically highly significant association (p=0.000) of 10-year risk of heart disease between two groups. There is a positive correlation (r=0.45, p<0.0001) between CIMT and risk of heart disease. Conclusion: Our study found that greater the CIMT, greater the risk of the heart of disease.
No takes yet. Share an insight, caveat, or question.
Mugada et al. (2019) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: