Key result
Ten-year glycemic control shows no correlation with CIMT in type 1 diabetes.
Why the study?
It was uncertain whether carotid intima-media thickness, a surrogate marker of cardiovascular disease, is associated with long-term glycemic control in individuals with type 1 diabetes.
Does long-term glycemic control correlate with carotid intima-media thickness in individuals with type 1 diabetes?
Population
508 individuals with type 1 diabetes, median age 46.1 years, median diabetes duration 30.4 years
Design
Cross-sectional retrospective sub-study of the Finnish Diabetic Nephropathy Study
Authors
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No immediate change to glycemic targets for carotid atherosclerosis in type 1 diabetes; leaves open age as dominant driver of early macrovascular changes.
Cross-Sectional (n=508)
No
Does long-term glycemic control correlate with carotid intima-media thickness in individuals with type 1 diabetes?
p-value: p=0.063
Long-term glycemic control is not correlated with carotid intima-media thickness in individuals with type 1 diabetes, suggesting early macrovascular atherosclerosis in this population is driven more by age than hyperglycemia.
Inkeri et al. (2023) conducted a cross-sectional in Type 1 diabetes (n=508). Long-term glycemic control (HbA1c) was evaluated on Correlation between long-term glycemic control (HbA1c-meanoverall) and carotid intima-media thickness (p=0.063). Long-term blood glucose control over 10 years showed no significant correlation with carotid intima-media thickness in individuals with type 1 diabetes (p=0.063).
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