Key result
Type 1 diabetes was associated with a significantly higher mean aggregate carotid intima-media thickness compared to healthy controls (0.6 mm vs 0.4 mm, p=0.000).
Why the study?
Is type 1 diabetes associated with increased carotid intima-media thickness (cIMT) compared to healthy controls in adolescents and young adults?
Population
80 subjects: 40 with type 1 diabetes and 40 normal healthy controls.
Design
Case-control
Authors
Loading...
May warrant closer CV surveillance in T1D youth; leaves open whether cIMT predicts events.
Case-Control (n=80)
Is type 1 diabetes associated with increased carotid intima-media thickness (cIMT) compared to healthy controls in adolescents and young adults?
Absolute Event Rate: 0.6% vs 0.4%
p-value: p=0.000
Adolescents and young adults with type 1 diabetes have significantly increased carotid intima-media thickness compared to healthy controls, indicating early subclinical atherosclerosis.
Abdelghaffar et al. (2005) conducted a case-control in Type 1 diabetes (n=80). Type 1 diabetes vs. Normal healthy controls was evaluated on Mean aggregate carotid intima-media thickness (cIMT) (p=0.000). Type 1 diabetes was associated with a significantly higher mean aggregate carotid intima-media thickness compared to healthy controls (0.6 mm vs 0.4 mm, p=0.000).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: