Key result
In patients with type 1 diabetes, the presence of microvascular complications was associated with significantly increased carotid intima-media thickness compared to those without complications (0.70 vs 0.63 mm; p=0.001).
Cross-Sectional (n=172)
Absolute Event Rate: 0.7% vs 0.63%
p-value: p=0.001
Increased carotid intima-media thickness in type 1 diabetic patients is associated with microvascular complications, suggesting a link between diabetic microangiopathy and early macrovascular disease.
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Association between microvascular complications and higher cIMT in type 1 diabetes supports shared vasculopathy pathways; hypothesis-generating and should not yet change practice.
Gül et al. (2010) conducted a cross-sectional in Type 1 diabetes mellitus (n=172). Microvascular complications (nephropathy and/or retinopathy) vs. Patients without microvascular complications was evaluated on Carotid intima-media thickness (CIMT) (p=0.001). In patients with type 1 diabetes, the presence of microvascular complications was associated with significantly increased carotid intima-media thickness compared to those without complications (0.70 vs 0.63 mm; p=0.001).
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