Key result
Diabetic retinopathy was associated with significantly greater carotid intima-media thickness compared to patients without retinopathy (0.95 mm vs 0.73 mm, P < 0.001).
Why the study?
Is the presence of retinopathy associated with increased carotid intima-media thickness in type 2 diabetic patients?
Cross-Sectional (n=154)
No
Is the presence of retinopathy associated with increased carotid intima-media thickness in type 2 diabetic patients?
Absolute Event Rate: 0.95% vs 0.73%
p-value: p=<0.001
In type 2 diabetic patients, the presence of retinopathy is significantly associated with increased carotid intima-media thickness, suggesting CIMT could be a useful noninvasive screening tool for vascular complications.
Diabetic retinopathy was associated with greater CIMT; hypothesis-generating for shared vasculopathy and requires prospective confirmation before clinical use.
BACKGROUND: This study was carried out in order to evaluate the relationship between retinopathy and carotid intima-media thickness (CIMT). MATERIALS AND METHODS: In a cross-sectional study, 154 diabetic patients who had a history of diabetic disease were evaluated in two equal groups of 77 patients with and without retinopathy, respectively. CIMT was evaluated in all of the patients. RESULTS: Mean age of the patients was 59.65 ± 9.37 years. Mean CIMT of all patients was 0.84 ± 0.18. CIMT of patients with retinopathy was significantly greater than patients without retinopathy (P < 0.001). CIMT also correlated with age, duration of diabetes, systolic blood pressure, blood urea nitrogen, and serum creatinine. CONCLUSION: CIMT may be used as a simple, available and noninvasive method for screening of macro and microvascular complication of diabetic patients.
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Dyani et al. (2015) conducted a cross-sectional in Type 2 Diabetes Mellitus (n=154). Diabetic retinopathy vs. No diabetic retinopathy was evaluated on Carotid intima-media thickness (CIMT) (p=<0.001). Diabetic retinopathy was associated with significantly greater carotid intima-media thickness compared to patients without retinopathy (0.95 mm vs 0.73 mm, P < 0.001).
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