A method was developed to prepare chicken gizzard heavy meromyosin retaining its light chains, demonstrating that its Mg-ATPase activity increases with phosphorylation and becomes calcium-insensitive.
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Biochemical data from avian smooth muscle HMM remain hypothesis-generating; extends myosin regulation models but leaves open mammalian and clinical translation.
Onishi et al. (1979) studied this question.
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