Potential Fluoxetine Chloride (Prozac) Toxicity in a Newborn

To the Editor. The relative safety of fluoxetine chloride (Prozac) when used during pregnancy has been recently addressed.1,2 However, little attention has been paid to its potential neurologic and hematologic side effects in the newborn. Spencer3described an infant exposed to fluoxetine who demonstrated symptoms suggestive of toxicity. We would like to describe an additional infant with potential fluoxetine toxicity. A 3020-gram boy was delivered at term to a 34-year-old mother who had obsessive-compulsive disorder treated with fluoxetine, 60 mg daily. …