Population
Normal rats (adult and newborn)
Comparison
Unilateral tenotomy of the gastrocnemius muscle… vs Contralateral limb muscles
Design
Preclinical
Authors
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Indicates possible contractile slowing in rapid hypertrophy; leaves open relevance to human cardiac or skeletal muscle.
Work-induced rapid hypertrophy of the soleus muscle in rats leads to a decrease in the specific activity of myosin ATPase, which depends on the rate of muscle hypertrophy.
Jablecki et al. (1973) studied this question.
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