Why the study?
Cortex-involved lesions are typically associated with embolic stroke commonly caused by AF, but the associations between cortex-involved stroke, vascular risk factors, and AF subtypes remained to be determined.
Is newly detected atrial fibrillation associated with cortex-involved ischemic stroke in acute ischemic stroke patients?
Population
243 acute ischemic stroke patients with AF at 20 Chinese hospitals
Comparison
Newly detected AF vs known AF across AF duration subtypes
Design
Prospective, multicenter cohort, cross-sectional imaging sub-study with blinded imaging review
Authors
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Newly detected AF was associated with cortex-involved stroke; leaves open whether AF subtypes guide targeted screening or secondary prevention.
Is newly detected atrial fibrillation associated with cortex-involved ischemic stroke in acute ischemic stroke patients?
Newly detected atrial fibrillation persistent for more than 24 hours is significantly associated with cortex-involved ischemic stroke, suggesting a cardioembolic mechanism for the index event.
Li et al. (2019) studied this question.
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