What question did this study set out to answer?

To review the phenotypic risk factors, prevalence, and therapeutic efficacy of continuous positive airway pressure (CPAP) for obstructive sleep apnoea/hypopnoea syndrome (OSAHS) in adults with Down syndrome.

December 1, 2016BreatheOpen Access

Obstructive sleep apnoea/hypopnoea syndrome in adults with Down syndrome

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To review the phenotypic risk factors, prevalence, and therapeutic efficacy of continuous positive airway pressure (CPAP) for obstructive sleep apnoea/hypopnoea syndrome (OSAHS) in adults with Down syndrome.
Narrative review examining recent subjective and objective studies on OSAHS prevalence and risk mechanisms in adults with Down syndrome.
Evaluation of clinical outcomes associated with continuous positive airway pressure (CPAP) intervention and current health surveillance practices.
OSAHS prevalence in adults with Down syndrome is estimated at 35% to 42%, up to ten times higher than the 2% to 4% reported in the general adult population.
Untreated comorbid OSAHS poses a 'double-hit' risk that may accelerate cognitive decline and cause emotional and behavioral disturbances.
Continuous positive airway pressure (CPAP) therapy leads to significant improvements in daytime function, subjective sleepiness, behavior, and cognitive function.

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Implication

Clinical review reveals high prevalence of obstructive sleep apnoea in adults with Down syndrome, highlighting the benefits of continuous positive airway pressure therapy.

Cite This Study

Elizabeth A. Hill (2016) studied this question.

synapsesocial.com/papers/6a727753b27f158178280c4e https://doi.org/10.1183/20734735.012116

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Implication

Clinical review reveals high prevalence of obstructive sleep apnoea in adults with Down syndrome, highlighting the benefits of continuous positive airway pressure therapy.

Obstructive sleep apnoea/hypopnoea syndrome in adults with Down syndrome

Key Points

Discussion

Implication

Cite This Study

Obstructive sleep apnoea/hypopnoea syndrome in adults with Down syndrome

Key Points

Discussion

Implication

Cite This Study

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