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May 1, 1991Journal of Biological ChemistryOpen Access

Heterologous combinations of heavy and light chains from botulinum neurotoxin A and tetanus toxin inhibit neurotransmitter release in Aplysia

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Authors

BPBernard PoulainCentre National de la Recherche ScientifiqueSMSumiko MochidaTokyo Medical UniversityUWUlrich WellerHelmholtz Centre for Environmental Research

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Cite This Study

Poulain et al. (1991) studied this question.

synapsesocial.com/papers/6a727ae5ac440176ef2ab2f9https://doi.org/10.1016/s0021-9258(18)92859-0
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A Study of the Mechanism of Internalisation of Tetanus Toxin by Primary Mouse Spinal Cord Cultures1987 · 60 citations
  2. 2Role of the heavy and light chains of botulinum neurotoxin in neuromuscular paralysis.1987 · 103 citations
  3. 3Isolated Light Chains of Botulinum Neurotoxins Inhibit Exocytosis1989 · 133 citations
  4. 4The complete sequence of botulinum neurotoxin type A and comparison with other clostridial neurotoxins.1990 · 231 citations
  5. 5Light chain of tetanus toxin intracellularly inhibits acetylcholine release at neuro‐neuronal synapses, and its internalization is mediated by heavy chain1989 · 89 citations