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April 1, 2002Archives of Surgery

The Effect of Comorbid Illness on Mortality Outcomes in Cardiac Surgery

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Why the study?

Do comorbid conditions increase the risk of in-hospital mortality in patients undergoing isolated coronary artery bypass graft surgery?

Population

27,239 consecutive patients undergoing isolated coronary artery bypass graft surgery

Comparison

Presence of comorbid conditions vs Absence of specific comorbid conditions

Design

Cohort

Follow-up

In-hospital

Authors

RCRobert A. CloughEastern Maine Medical Center

Discussion

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Implication

Informs preoperative risk stratification for isolated CABG; leaves open whether comorbidity optimization reduces mortality.

Structured PICO

Do comorbid conditions increase the risk of in-hospital mortality in patients undergoing isolated coronary artery bypass graft surgery?

P
Population
27,239 consecutive patients undergoing isolated coronary artery bypass graft surgery
I
Intervention
Presence of comorbid conditions (including hypertension, diabetes, obesity, vascular disease, chronic obstructive pulmonary disease, cancer, dialysis-dependent renal failure, liver disease, and dementia)
C
Comparator
Absence of specific comorbid conditions
O
Outcome
In-hospital mortality ratehard clinical

Comorbid conditions, particularly dialysis-dependent renal failure, vascular disease, COPD, peptic ulcer, and diabetes, independently increase the risk of in-hospital mortality following isolated CABG.

Cite This Study

Robert A. Clough (2002) studied this question.

synapsesocial.com/papers/6a727e0ff44fa9f079dff533https://doi.org/10.1001/archsurg.137.4.428
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Obesity and Risk of Adverse Outcomes Associated With Coronary Artery Bypass Surgery1998 · 250 citations
  2. 2Stratification of morbidity and mortality outcome by preoperative risk factors in coronary artery bypass patients. A clinical severity score1992 · 184 citations
  3. 3Identification of preoperative variables needed for risk adjustment of short-term mortality after coronary artery bypass graft surgery1996 · 310 citations
  4. 4Assessing the Outcomes of Coronary Artery Bypass Graft Surgery: How Many Risk Factors Are Enough? fn1fn1Dr. Naylor is supported by a Career Scientist Award from the Ontario Ministry of Health, Toronto, Ontario, Canada. This work was supported by an operating grant from the Sunnybrook Trust for Medical Research, North York, Ontario, Canada.fn2fn2To discuss this article on-line, visit the ACC Home page at www.acc.org/membersand click on the JACC Forum1997 · 135 citations
  5. 5A Regional Intervention to Improve the Hospital Mortality Associated With Coronary Artery Bypass Graft Surgery1996 · 728 citations