This review highlights the importance of targeting systolic blood pressure and utilizing low-dose diuretics in the management of hypertension in older adults, including those over 80.
Supports hypertension treatment in octogenarians; leaves open optimal targets and regimens in contemporary practice.
Recent studies have now demonstrated that it is more important to focus on the SBP level than the DBP level in older persons. In addition, recent studies indicate that persons over age 80 still derive substantial benefit from treating ISH or DH. Also, studies now show that low-dose diuretics have a more favorable impact on subsequent coronary heart disease rates than was previously demonstrated. Finally, although caution is urged, it is unlikely the J-shaped relationship between treated DBP or SBP and subsequent mortality is due to overly aggressive treatment of high blood pressure. Table 4 provides the authors' guidelines for treating older persons with high blood pressure.
No takes yet. Share an insight, caveat, or question.
Applegate et al. (1992) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: