Why the study?
Do ethnicity, gender, and family history of early myocardial infarction affect hemodynamic responses to laboratory stressors in children?
Do ethnicity, gender, and family history of early myocardial infarction affect hemodynamic responses to laboratory stressors in children?
Children of Black ethnicity or with a family history of early myocardial infarction exhibit exaggerated hemodynamic responses to physical stressors, suggesting early physiological markers of cardiovascular risk.
May flag early CV vulnerability in Black children and those with family history; leaves open predictive value and intervention targets.
Relationship among ethnicity, gender, grandparents' histories of early myocardial infarction, and hemodynamic responses to forehead cold and treadmill exercise were examined in 87 6-to-8-year-olds (57 White, 30 Black). Boys had greater increases in systemic vascular resistance and decreases in cardiac index to forehead cold. Girls had greater increases and quicker recovery in heart rate to dynamic exercise. Blacks had greater increases and slower recovery in diastolic pressure to exercise and forehead cold. Blacks showed greater increases and slower recovery in systemic vascular resistance to forehead cold. Positive-family-history children had greater increases in diastolic pressure and systemic vascular resistance to forehead cold and greater diastolic pressure increases to exercise. Positive-family-history Blacks had greater increases in systolic pressure to exercise and slower recovery than all other groups.
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Treiber et al. (1993) studied this question.
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