Why the study?
While most studies of fluoxetine focused on cardio/cerebrovascular systems, knowledge regarding its vasomotor effect remained limited.
Does fluoxetine have a vasoactive effect on rat thoracic aorta smooth muscle?
Does fluoxetine have a vasoactive effect on rat thoracic aorta smooth muscle?
Fluoxetine exhibits a dose-dependent vasodilator effect on rat thoracic aorta smooth muscle.
Animal data suggest fluoxetine may promote vasodilation; leaves open translation to human cardiovascular therapy.
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Işık et al. (2022) studied this question.
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