Why the study?
To compare long-term clinical and radiographic outcomes among five sets of remission criteria (four clinical and one ultrasound-based) in rheumatoid arthritis patients in a clinical care setting.
Do more stringent remission criteria (SDAI, CDAI, Boolean, or Ultrasound) improve long-term clinical and radiographic outcomes compared to DAS28-ESR remission in patients with established Rheumatoid Arthritis?
Population
Eighty-seven RA patients in remission (DAS28-ESR <2.6)
Comparison
Five remission criteria: DAS28-ESR<2.6, SDAI<3.3, CDAI<2.8, Boolean criteria, and score Power Doppler=0
Design
Cohort study
Follow-up
5 years
Authors
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Different remission criteria show varying associations with RA radiographic progression; leaves open which best guide long-term care.
Do more stringent remission criteria (SDAI, CDAI, Boolean, or Ultrasound) improve long-term clinical and radiographic outcomes compared to DAS28-ESR remission in patients with established Rheumatoid Arthritis?
In patients with established rheumatoid arthritis, standard DAS28-ESR remission provides comparable long-term clinical and radiographic outcomes to more stringent clinical criteria, though ultrasound-defined remission is associated with the least structural damage progression.
Ramírez et al. (2020) studied this question.
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