Key result
Acute pancreatitis triggers fatal noncardiogenic pulmonary edema and heart failure in canine cardiac disease.
Case Report (n=1)
No
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Case report demonstrates acute pancreatitis-induced noncardiogenic pulmonary edema in a dog with cardiac disease, highlighting noncardiac mechanisms of lung injury.
Acute pancreatitis and cardiac disease were diagnosed in a dog with pulmonary edema. The early clinical course and initial thoracic radiographs suggested that the pulmonary edema was noncardiogenic. The late clinical course was complicated by heart failure. The dog died, and a necropsy was performed. Histologically, an acute, severe capillary-alveolar membrane lesion was found in the lungs. Review of the human medical literature indicated that respiratory complications, including pulmonary edema, are commonly recognized in people with acute pancreatitis. Furthermore, in acute pancreatitis of human beings, the existence of specific mechanisms of pulmonary injury is suspected. Retrospective consideration of this case suggested that the initial pulmonary edema was induced by acute pancreatitis.
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Lees et al. (1978) conducted a case report in Pulmonary edema with acute pancreatitis and cardiac disease (n=1). Acute pancreatitis was evaluated on Death and histological capillary-alveolar membrane lesion. Acute pancreatitis in 1 dog with cardiac disease induced noncardiogenic pulmonary edema with a severe capillary-alveolar membrane lesion, followed by heart failure and death.
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