Population
4,120 major orthopaedic surgery patients from 13 studies who received pharmacological prophylaxis, underwent…
Design
Meta-analysis
Follow-up
at least four weeks
Authors
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Supports forgoing extended prophylaxis after negative venography; confirms low post-discharge symptomatic VTE risk in major orthopaedic surgery.
Major orthopaedic surgery patients discharged with a negative venography have a low incidence of clinically overt venous thromboembolism, suggesting extended pharmacological prophylaxis is not justified in this population.
Ricotta et al. (1996) studied this question.
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