Why the study?
Does Roux-en-Y gastric bypass acutely improve insulin sensitivity in premenopausal women with metabolic syndrome?
Population
19 premenopausal women with metabolic syndrome, mean age 35.3 years, mean BMI 45.50 kg/m2. Included 6 with…
Comparison
Roux-en-Y gastric bypass either alone or… vs Baseline (preoperative state)
Design
Cohort
Follow-up
4.5 weeks
Authors
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Fasting HOMA-IR gains after RYGB should not be equated with peripheral insulin sensitivity changes; leaves open acute mechanisms in metabolic syndrome.
Does Roux-en-Y gastric bypass acutely improve insulin sensitivity in premenopausal women with metabolic syndrome?
Roux-en-Y gastric bypass acutely improves fasting glucose metabolism and HOMA-IR independent of changes in peripheral insulin sensitivity.
Lima et al. (2010) studied this question.
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