Deep Learning-based Research Model of COVID-19

Coronavirus disease 2019 is an acute infectious pneumonia. The initial symptoms in infected patients are mostly fatigue, dry cough and fever, before gradually developing into more severe symptoms such as breathing difficulties. At present, the route of transmission, occurrence and development, vaccine research and development, and treatment methods of the new coronavirus pneumonia have not yet been fully clarified. Animal models are widely used to study and clarify the pathogenesis of various human diseases but there is currently no suitable animal model that can fully simulate the clinical manifestations of patients with new coronavirus pneumonia. Therefore, it is very important to establish and screen potentially suitable animal models for the study into the new coronavirus pneumonia. This article reviews the current research status of animal models of new coronavirus pneumonia, and compares the basis of different animal models for new corona pneumonia. The advantages and disadvantages of the research have sorted out the latest research progress of different types of animals in the new coronavirus pneumonia animal model, in order to provide references for the in-depth development of experimental animal models on novel coronavirus pneumonia.