Defects were created in the tooth-supporting bone of six beagle dogs. Biodegradable tricalcium phosphate was compared to cancellous marrow as a treatment method. The findings indicated that ankylosis and resorption of the tooth can occur when using marrow. The ceramic-filled defects healed slower; but the material itself was well tolerated by the tissues, initiated new bone formation, filled in the defect, and has good potential for the treatment of advanced periodontitis.
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Levin et al. (1975) studied this question.
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