July 18, 1990JAMA

The Association of Borderline Hypertension With Target Organ Changes and Higher Coronary Risk

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Why the study?

Does borderline hypertension associate with target organ changes and higher coronary risk in healthy young adults?

Population

946 healthy subjects aged 18 through 38 years from the Tecumseh project

Comparison

Borderline hypertension vs Normotensive subjects

Design

Cohort

Authors

SJStevo JuliusUppsala University

Discussion

Member takes

Implication

May support closer monitoring of borderline hypertension; hypothesis-generating for intervention trials in young adults.

Structured PICO

Does borderline hypertension associate with target organ changes and higher coronary risk in healthy young adults?

Population

946 healthy subjects aged 18 through 38 years from the Tecumseh project

Intervention

Borderline hypertension (clinic blood pressure readings higher than 140/90 mm Hg, mean 130/94 mm Hg)

Comparator

Normotensive subjects

Outcome

Target organ changes (minimal forearm resistance, stroke index, ventricular diastolic relaxation) and coronary risk factors (cholesterol, triglycerides, HDL, insulin, overweight)surrogate

Borderline hypertension in young adults is associated with early target organ damage and adverse coronary risk factor profiles, indicating it is neither transient nor innocuous.

Cite This Study

Stevo Julius (1990) studied this question.

synapsesocial.com/papers/6a72995f6c240de38cdc6adf https://doi.org/10.1001/jama.1990.03450030078036

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The Association of Borderline Hypertension With Target Organ Changes and Higher Coronary Risk

Discussion

Member takes

Implication

Structured PICO

Cite This Study

The Association of Borderline Hypertension With Target Organ Changes and Higher Coronary Risk

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider