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Objective: To describe and evaluate a community- and theory-driven multilevel opioid overdose fatality prevention intervention for Black Indianapolis communities for 2022-2025. Methods: A community-driven opioid overdose fatality prevention project was designed based on Community Coalition Action Theory, the Citizen Health Care Model, and Legal Epidemiology. The intervention was implemented in inner-city Indianapolis (zip code areas 46202, 46205, 46208, 46218) with cluster-matched comparison areas in Indiana (46408, 46410, 46628, 46806). Data were collected in Indiana, U.S.A., in 2022-2025. Evaluation included mortality analysis and community probability surveys in Year 1 and 3. Conclusions: Similar community- and theory-driven multi-level interventions may be effective in reducing overdose mortalities in the Black communities.
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Seo et al. (2026) studied this question.
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