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October 1, 2000Human Gene Therapy

Treatment of a Lysosomal Storage Disease, Mucopolysaccharidosis VII, with Microencapsulated Recombinant Cells

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Authors

CRColin J.D. RossUniversity of British ColumbiaLBLaila K. BastedoMcMaster UniversitySMStefan A. MaierUniversity of Stuttgart

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Ross et al. (2000) studied this question.

synapsesocial.com/papers/6a729b5cf44fa9f079e0065chttps://doi.org/10.1089/104303400750001426
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Delivery of Recombinant Gene Products to the Central Nervous System with Nonautologous Cells in Alginate Microcapsules1999 · 45 citations
  2. 2Cross-Correction of β-Glucuronidase Deficiency by Retroviral Vector-Mediated Gene Transfer1994 · 51 citations
  3. 3Sustained Production of β-Glucuronidase from Localized Sites after AAV Vector Gene Transfer Results in Widespread Distribution of Enzyme and Reversal of Lysosomal Storage Lesions in a Large Volume of Brain in Mucopolysaccharidosis VII Mice1999 · 139 citations
  4. 4Disappearance of lysosomal storage in spleen and liver of mucopolysaccharidosis VII mice after transplantation of genetically modified bone marrow cells1993 · 79 citations
  5. 5Behavioural abnormalities in a murine model of a human lysosomal storage disease1993 · 28 citations