Lysosomal Enzymes and Their Receptors

This review is limited to discussion of synthesis and transport of lysosomal in mammalian tissues. We focus on the processing of the oligosaccharides lysosomal enzymes, on the mannose 6-phosphate-specific receptor (MPR), and on its role in the transport of lysosomal enzymes. The transport of enzymes and the function of mannose 6-phosphate-specific receptors been the subject of recent reviews (3-5).