Why the study?
Does prophylactic digitalization reduce supraventricular arrhythmias in patients undergoing aortocoronary bypass surgery?
Does prophylactic digitalization reduce supraventricular arrhythmias in patients undergoing aortocoronary bypass surgery?
Prophylactic digitalization significantly reduces the incidence of supraventricular arrhythmias following aortocoronary bypass surgery without evidence of toxicity.
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Supports prophylactic digitalization before aortocoronary bypass; confirms supraventricular arrhythmia reduction in this RCT without toxicity.
One hundred and twenty patients undergoing aortocoronary bypass procedures were randomly placed into control and digitalized groups. All were initially in normal sinus rhythm and without evidence of congestive heart failure. Supraventricular arrhythmias occurred in 17 of 66 controls and in only three of 54 digitalized patients (P less than 0.01). There was no evidence of digitals toxicity. Based on this evidence we recommend prophylactic digitalization for patients having aortocoronary bypass operations.
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Johnson et al. (1976) studied this question.
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