Not an Uncommon Tumor: Brown Tumor: Case Series

Brown tumors are uncommon skeletal manifestations of prolonged hyperparathyroidism and frequently mimic primary bone tumors on imaging and histopathology. We report the case of two patients with Brown tumors involving long bones, both initially diagnosed as primary bone tumors. Diagnostic discordance and atypical disease progression prompted biochemical evaluation, revealing hyperparathyroidism. Brown tumors should be considered in giant cell-rich bone lesions, particularly when clinicoradiological and histopathological findings are discordant. Early biochemical assessment can prevent unnecessary surgical intervention.