A lysosomal targeting signal in the cytoplasmic tail of the beta chain directs HLA-DM to MHC class II compartments.

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1A monoclonal antibody (anti-Tac) reactive with activated and functionally mature human T cells. I. Production of anti-Tac monoclonal antibody and distribution of Tac (+) cells.1981 · 1,337 citations
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4. 4The cytoplasmic domain mediates localization of furin to the trans-Golgi network en route to the endosomal/lysosomal system.1994 · 170 citations
5. 5The MHC class II-associated invariant chain contains two endosomal targeting signals within its cytoplasmic tail1993 · 206 citations