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A green protocol involving novel three-component one-pot cyclocondensation reactions of 2- amino-4-aryl-thiazoles, aromatic aldehydes and ammonium thiocyanate under solvent-free microwave irradiation (MWI) conditions expeditiously yields thiazolo-s-triazine nucleobases, which afford the corresponding pyrano N-nucleosides on I2 promoted glycosylation with 1,2,3,4-tetra-O-acetyl- β-D-ribo- /xylopyranose under MWI followed by deacetylation.
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Yadav et al. (2007) studied this question.
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