What question did this study set out to answer?

To determine how systemic hemodynamics and visceral organ blood flow distribution alter during steady-state versus exhaustive treadmill exercise in conscious dogs.

June 1, 1976Journal of Applied Physiology

Visceral blood flow distribution during exercise to exhaustion in conscious dogs

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Population

9 conscious dogs

Comparison

Exercise to exhaustion vs Resting/control state

Design

Preclinical

Follow-up

average of 35 min

Authors

TST. M. SandersID Genomics (United States)RWRudolf A. WernerJohns Hopkins University CBC. M. BloorUniversity of Minnesota

Discussion

Member takes

Implication

Splanchnic flow redistribution varies by exercise intensity in animals; leaves open translation to human hemodynamics or practice.

Key Points

To determine how systemic hemodynamics and visceral organ blood flow distribution alter during steady-state versus exhaustive treadmill exercise in conscious dogs.
Evaluated 9 conscious dogs running on a treadmill (5–13 km/h at 8–15% grade) during steady-state (80% maximum heart rate) and exhaustive exercise (running until collapse).
Monitored heart rate, mean aortic pressure, cardiac output, and stroke volume using implanted probes and catheters, while measuring organ blood flow distribution using microspheres.
All systemic hemodynamic parameters increased significantly during exercise (P < 0.05), but stroke volume and aortic pressure did not exceed steady-state values during exhaustive exercise.
Blood flow to the liver, stomach, and intestines declined during steady-state exercise and returned to resting control levels during exhaustive exercise, whereas splenic blood flow declined progressively.
Renal and pancreatic blood flows showed no statistically significant changes during either steady-state or exhaustive exercise.

Structured PICO

Population

9 conscious dogs

Intervention

Exercise to exhaustion (running 5-13 km/h on a treadmill at 8-15% grade for an average of 35 min)

Comparator

Resting/control state

Outcome

Changes in organ blood flow (OBF) distribution and systemic hemodynamics (heart rate, mean aortic pressure, cardiac output, and stroke volume)surrogate

The effect of exercise on organ blood flow depends on exercise severity, and splanchnic organs do not respond homogeneously to exercise.

Cite This Study

Sanders et al. (1976) studied this question.

synapsesocial.com/papers/6a72a549fe4101aa97e0e617 https://doi.org/10.1152/jappl.1976.40.6.927

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Visceral blood flow distribution during exercise to exhaustion in conscious dogs

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Visceral blood flow distribution during exercise to exhaustion in conscious dogs

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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