Why the study?
Does elevated serum IL-6 predict the incidence of cardiovascular events in patients with type-2 diabetes without structural heart disease?
Population
82 patients with type-2 diabetes without structural heart disease, mean age 60 ± 12 years, 48 males.
Comparison
Elevated serum interleukin-6 levels vs Non-high IL-6 concentration (≤2.6 pg/mL)
Design
Cohort
Follow-up
mean 3.4 ± 2.0 years
Authors
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Elevated IL-6 may support risk stratification in T2D; hypothesis-generating for targeted therapies, requiring prospective validation.
Does elevated serum IL-6 predict the incidence of cardiovascular events in patients with type-2 diabetes without structural heart disease?
Elevated serum IL-6 concentration independently predicts future major adverse cardiovascular events in patients with type-2 diabetes without structural heart disease.
Tetsuji Shinohara (2012) studied this question.
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