Answers are grounded in this paper and cite their sources.
The alkylhalide‐halide association ions, [RX 2 ] − that are observed in the negative chemical ionization mass spectra of alkyl halides appear to be directly related to the corresponding S N 2 transition states in solution. ‘Frontside’ association of halide ions with bridgehead alkyl halides does not occur in our system. The Change in heats and entropies of association for the chloromethane series is consistent with delocalization in the [RX] 2 − ions.
No takes yet. Share an insight, caveat, or question.
Dougherty et al. (1974) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: