Key result
ECG-triggered 3D-radial 23Na-MRI achieves a myocardial SNR of ~10 in under 18 minutes.
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Sodium MRI has the potential to differentiate viable and non-viable infarcted myocardium. The accurate quantification of the total sodium content requires imaging techniques with ultra short echo times below 0.5 ms. We present a 3D-radial projection technique which allows the acquisition of ECG-triggered sodium images of the human heart with echo times of 0.4 ms. A 3D-data set of the heart of a volunteer was acquired within less than 18 min on a clinical scanner (1.5 T), achieving a SNR of 10 in the myocardium with an isotropic resolution of 10 mm. This technique provides a tool for clinical studies of ischemic heart diseases.
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Jerec̆ić et al. (2002) studied Ischemic heart disease (healthy volunteer tested) (n=1). 3D-radial projection 23Na-MRI was evaluated on Myocardial signal-to-noise ratio (SNR) and spatial resolution. ECG-triggered 3D-radial projection 23Na-MRI at 1.5 T acquired a human heart dataset in <18 min, achieving a myocardial SNR of 10 with 10 mm isotropic resolution.
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