What question did this study set out to answer?

Determine whether the synthetic fluorinated sugar analogue 3-fluorosialic acid inhibits the catalytic activity of N-acetylneuraminic acid aldolase.

December 1, 1964Biochemistry

Inhibition of N-Acetylneuraminic Acid Aldolase by 3-Fluorosialic Acid*

View Full Paper

Ask AI

Bookmark

Determine whether the synthetic fluorinated sugar analogue 3-fluorosialic acid inhibits the catalytic activity of N-acetylneuraminic acid aldolase.
Assayed the cleavage and catalytic activity of N-acetylneuraminic acid aldolase in the presence of 3-fluorosialic acid in vitro.
Demonstrated that 3-fluorosialic acid acts as an effective inhibitor of N-acetylneuraminic acid aldolase.

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

Biochemical assay demonstrates inhibition of N-acetylneuraminic acid aldolase by 3-fluorosialic acid, indicating potential for targeted enzyme regulation.

Cite This Study

Gantt et al. (1964) studied this question.

synapsesocial.com/papers/6a72b29475498292b70bacea https://doi.org/10.1021/bi00900a029

View Full Paper

Ask AI

Bookmark

Implication

Biochemical assay demonstrates inhibition of N-acetylneuraminic acid aldolase by 3-fluorosialic acid, indicating potential for targeted enzyme regulation.

Inhibition of N-Acetylneuraminic Acid Aldolase by 3-Fluorosialic Acid*

Key Points

Discussion

Implication

Cite This Study

Inhibition of N-Acetylneuraminic Acid Aldolase by 3-Fluorosialic Acid*

Key Points

Discussion

Implication

Cite This Study

Also Consider

Also Consider