Why the study?
Do Apolipoprotein E phenotypes E4/4 or E4/3 increase the prevalence of coronary heart disease in men with non-insulin dependent diabetes?
Do Apolipoprotein E phenotypes E4/4 or E4/3 increase the prevalence of coronary heart disease in men with non-insulin dependent diabetes?
Apolipoprotein E phenotypes E4/4 and E4/3 are associated with a significantly higher prevalence of coronary heart disease in men with non-insulin dependent diabetes.
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E4 phenotypes associated with higher CHD prevalence in diabetic men; hypothesis-generating and should not yet change practice.
Laakso et al. (1991) studied this question.
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