Incidence, characteristics, determinants, and prognostic impact of recurrent syncope
Why the study?
The study aimed to characterize recurrent syncope, including sex-specific aspects, and determine its impact on death and major adverse cardiovascular events.
Does recurrent syncope increase the risk of death and major adverse cardiovascular events in patients presenting to the emergency department with syncope?
Population
1790 patients ≥40 years presenting to the ED with syncope within the last 12 h
Comparison
Recurrent syncope vs no recurrent syncope
Design
International multicentre observational cohort study
Follow-up
24 months
Authors
Discussion
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Member takes
Implication
Recurrent syncope was associated with higher death and MACE risk; leaves open whether time-dependent effects warrant targeted monitoring in observational cohorts.
Structured PICO
Does recurrent syncope increase the risk of death and major adverse cardiovascular events in patients presenting to the emergency department with syncope?
P
Population
1,790 patients ≥40 years presenting to the emergency department with a syncopal event within the last 12 hours in a large international multicentre study.
I
Intervention
Recurrent syncope (exposure)
C
Comparator
No recurrent syncope
O
Outcome
Incidence of recurrent syncope, death, and major adverse cardiovascular events (MACE) over 24 monthshard clinical
Recurrent syncope is common (20% at 24 months) and is associated with a significantly increased risk of subsequent death and major adverse cardiovascular events.
Cite This Study
Zimmermann et al. (2020) studied this question.