Why the study?
Can ketamine administration for sedation cause cardiopulmonary arrest in pediatric patients following operative correction of tetralogy of Fallot?
Can ketamine administration for sedation cause cardiopulmonary arrest in pediatric patients following operative correction of tetralogy of Fallot?
Ketamine administration for sedation in post-operative pediatric patients with congenital heart disease may be associated with severe adverse events such as cardiopulmonary arrest.
May trigger cardiopulmonary arrest with ketamine for drain removal post-TOF repair; leaves open safety questions in postoperative congenital heart disease.
Due to its hemodynamic stability, ketamine is a commonly used anesthetic agent for sedation during small procedures in the critical care unit. We report a case of an 8-year-old girl, previously diagnosed with tetralogy of Fallot who presented for operative correction of the congenital anomaly. She underwent a successful operation and recovered smoothly. On the second postoperative day, and upon removal of a chest drain with the use of ketamine for sedation, the patient suffered cardiopulmonary arrest. After repeated cycles of resuscitation, the patient returned to spontaneous circulation.
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Abdalla et al. (2024) studied this question.
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