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A 42-year-old abuser of intravenous drugs developed fulminant aortic insufficiency necessitating a prosthetic valve replacement. Trichosporon cutaneum was isolated from the surgical specimen. The patient received a total of 3,195 g of amphotericin B, and 148 g of 5-fluorocytosine during his four-month hospitalization. He manifested no additional signs of persistent fungal infection, but died one year later from an intracerebral hemorrhage.
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Brahn et al. (1982) studied this question.
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