Why the study?
Does precurarization with small doses of non-depolarizing muscle relaxants cause serious reactions in patients?
Does precurarization with small doses of non-depolarizing muscle relaxants cause serious reactions in patients?
Precurarization with small doses of non-depolarizing muscle relaxants can cause serious reactions, emphasizing the need for weight-based dosing and awareness of hypersensitivity.
Clinicians should remain vigilant for reactions to precurarization; case reports leave open the true incidence and risk factors.
Four case histories are presented illustrating the unpleasant and serious reactions that may follow precurarization with small doses of non-depolarizing muscle relaxants. The importance of preoperative information, the necessity of relating the dose of the precurarizing drug to the weight of the patient and the possibility of hypersensitivity to this drug are emphasized.
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Engbæk et al. (1984) studied this question.
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