Why the study?
Accurate renal function assessment is essential in hospitalized elderly patients, but few studies have examined the accuracy of Cockcroft-Gault estimates of creatinine clearance compared with measured clearance in this population.
Does Cockcroft-Gault estimation accurately correlate with measured creatinine clearance in hospitalized elderly patients?
Population
90 hospitalized patients aged 65 years and older with 8- or 24-hour urine collections
Comparison
Cockcroft-Gault estimates of CrCl vs measured CrCl
Design
Single-center retrospective observational cohort study
Authors
Loading...
C-G estimates differed significantly from measured CrCl in hospitalized elderly; leaves open whether measured clearance should guide dosing in this group.
Does Cockcroft-Gault estimation accurately correlate with measured creatinine clearance in hospitalized elderly patients?
Cockcroft-Gault estimates of creatinine clearance vary significantly from measured clearance in hospitalized elderly patients, suggesting potential inaccuracies in renal function assessment.
Lavelle et al. (2020) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: