Why the study?
The study investigated intimal growth in arteries induced by hemodynamical shear stress by coupling hemodynamics simulations to mathematical descriptions of atherosclerosis.
Population
Three distinct arterial cross section geometries in a computational model
Comparison
Annular vs non-annular cross section geometries
Design
Finite element simulation study
Authors
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Shear-dependent intimal growth model in layered arteries; hypothesis-generating and requires in vivo validation before clinical use.
This computational model demonstrates how arterial geometry influences hemodynamically-induced intimal thickening, providing a framework for coupling hemodynamics simulations to mathematical descriptions of atherosclerosis.
Mukherjee et al. (2024) studied this question.
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