This 1959 essay highlights early arguments for the prophylactic use of antihypertensive drugs to prevent heart disease.
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Early arguments for antihypertensive prophylaxis in heart disease extend historical context; leaves open validation against modern randomized evidence.
This short essay was part of a collection of papers on the prevention and control of heart disease originally presented at the eighty-seventh annual meeting of the American Public Health Association in October 1959. In it, Freis argued that hypertension was a major contributing factor in heart disease and antihypertensive drugs offered considerable prophylactic value in its treatment.
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Edward D. Freis (1960) studied this question.
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