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December 8, 2005Science

Increase in Activity During Calorie Restriction Requires Sirt1

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Authors

DCDanica ChenUniversity of California SystemASAndrew D. SteeleCalifornia State Polytechnic UniversitySLSusan LindquistNorthwestern University

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Chen et al. (2005) studied this question.

synapsesocial.com/papers/6a72c196c2d7c30908274684https://doi.org/10.1126/science.1118357
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Requirement of NAD and SIR2 for Life-Span Extension by Calorie Restriction in Saccharomyces cerevisiae2000 · 1,786 citations
  2. 2Sir2 mediates longevity in the fly through a pathway related to calorie restriction2004 · 1,367 citations
  3. 3The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms1999 · 2,288 citations