ZO-1 regulates gap junction localization via association with the N-cadherin multiprotein complex, which is crucial for stable localization of adherens and gap junctions at the intercalated disk.
No takes yet. Share an insight, caveat, or question.
Hypothesis-generating for ZO-1 in ICD integrity; leaves open arrhythmia relevance without mammalian validation.
Palatinus et al. (2010) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: