Why the study?
Does implantable cardioverter defibrillator (ICD) therapy improve survival and prevent sudden cardiac death in survivors of ventricular tachycardia-ventricular fibrillation (VT-VF)?
Does implantable cardioverter defibrillator (ICD) therapy improve survival and prevent sudden cardiac death in survivors of ventricular tachycardia-ventricular fibrillation (VT-VF)?
ICD therapy is a highly effective and cost-effective intervention for preventing sudden cardiac death in survivors of VT-VF compared to antiarrhythmic drugs or surgery.
Among the various therapy options for survivors of ventricular tachycardia-ventricular fibrillation (VT-VF), the implantable cardioverter defibrillator (ICD) seems most promising. It reliably terminates VT-VF and thus significantly impacts sudden cardiac death (SCD) survival. It is more effective than any of the known antiarrhythmic drugs in prevention of SCD, particularly among survivors of cardiac arrest. Compared to VT surgery, the ICD therapy can be offered to a larger pool of patients and can be placed at a lower surgical risk. With proper patient selection, ICD therapy is of major benefits to its recipients since it markedly reduces the chances of VT-VF related mortality; the main cause of premature death in this population. The ICD therapy is cost effective when compared to other medical interventions and could be more so if the implant is carried out early in the course of VT-VF management.
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Akhtar et al. (1993) studied this question.
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