Key result
Large-artery stroke is linked to higher cholesterol, triglycerides, and apoB at 6 months post-onset.
Observational (n=131)
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We determined plasma lipid and lipoprotein concentrations in 131 patients (95 males, 36 females, mean age 71 years) 6 months after acute stroke onset. Compared to a reference population, the alterations of plasma lipid concentrations in stroke patients were moderate. However, the stroke patients had higher levels of triglyceride and lipoprotein (a) and lower concentrations of cholesterol, high density lipoprotein cholesterol and low density lipoprotein cholesterol. Patients with different subtypes of stroke showed significant differences when compared with each other by analysis of covariance (with adjustment for age, sex, smoking, hypertension and diabetes). Patients with carotid or vertebral artery disease had the higher levels of cholesterol, triglyceride and apolipoprotein B, whereas high density lipoprotein triglyceride concentrations were higher in patients with cardioembolic infarcts.
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Lindgren et al. (1992) conducted an observational in Acute stroke (n=131). Stroke subtypes (carotid/vertebral artery disease vs cardioembolic infarcts) vs. Reference population and other stroke subtypes was evaluated on Plasma lipid and lipoprotein concentrations. Stroke subtypes differed significantly in plasma lipids 6 months post-onset (N=131), with higher cholesterol, triglycerides, and apoB in carotid or vertebral artery disease.
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